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Core Facilities

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Core Facilities are research platforms that provide access to specialized equipment, expertise, training, services, technologies, and scientific and technical personnel. These facilities are accessible to multiple investigators, including those external to º«¹úÂãÎè, and are a pivotal part of º«¹úÂãÎè’s research infrastructure, providing resources that allow groundbreaking science to happen. 

º«¹úÂãÎè Core Facilities are listed according to fields of expertise and appear multiple times if their services support more than one field.

Arts and Society

Centre for Interdisciplinary Research in Music, Media and Technology (CIRMMT)

Scientific Director: Fabrice Marandola
Faculty: Schulich School of Music

As a research service within CIRMMT, the platform offers cutting-edge equipment and expert technical support for integrated studies in music, acoustics, cognitive science, engineering, digital media, and performance sciences.Ìý

Keywords:Ìýsound, acoustics, digital media, performance sciencesÌý

Big Data and Computation

Canadian Centre for Computational Genomics (C3G)

Scientific Director: Guillaume Bourque
Faculty: Medicine and Health Sciences

The C3G platform provides access to highly qualified bioinformatics and IT personnel who deliver customized data analyses, software development, data portals, computing infrastructure and training services.

Keywords: genomics, bioinformatics, data analysis, software development, HPC

NeuroHub

Scientific Director: Jean-Baptiste Poline
Faculty: Medicine and Health Sciences

NeuroHub connects neuroscience with big data management. This unique platform allows users to collect, store and share data with colleagues or the community and to run complex tools and pipelines on high performance computing infrastructure.Ìý

Keywords: data management, data storage, computing, neuroscienceÌý

Cells and Tissues

Histology Innovation Platform

Scientific Director: Katie Cockburn
Faculty: Medicine and Health Sciences

The Histology Innovation Platform provides expertise, state-of-the-art technology, and efficient workflows in histological tissue processing, analysis, and interpretation.Ìý

Keywords:Ìýtissue, immunohistochemistry, tissue microarray, staining, sectioningÌý

Single Cell Imaging and Mass Cytometry Platform (SCIMAP)

Scientific Director: Logan Walsh
Faculty: Medicine and Health Sciences

SCIMAP provides advanced mass cytometry services for both liquid samples and tissue sections. The platform uses unique, well-validated antibody panels conjugated with heavy metals, enabling the simultaneous identification of over 40 markers on single cells.

Keywords:Ìýspatial biology, mass cytometry, antibody panels, marker profiling

Flow Cytometry Core Facility (FCCF)

Scientific Director: Jorg Fritz
Faculty: Medicine and Health Sciences

The Core facility provides instrumentation and technical assistance to perform laser-based flow cytometric analysis, as well as providing an operator-based cell sorting service.Ìý

Keywords:Ìýcells, immunohistochemistry, tissue microarray, staining, sectioningÌý

Early Drug Discovery Unit (EDDU)

Scientific Director: Thomas Durcan
Faculty: Medicine and Health Sciences

The EDDU uses patient-derived iPSCs to create 2D and 3D brain models, including organoids. They provide these materials and expertise to researchers for understanding and treating brain disorders, as well as for translational research and preclinical therapies.

Keywords:Ìýstem cells, transgenics, CRISPR, brain organoids

Drugs and Therapeutics

Early Drug Discovery Unit (EDDU)

Scientific Director:ÌýThomas DurcanÌý
Faculty: Medicine and Health Sciences

The EDDU uses patient-derived iPSCs to create 2D and 3D brain models, including organoids. They provide these materials and expertise to researchers for understanding and treating brain disorders, as well as for translational research and preclinical therapies.Ìý

Keywords:Ìýstem cells, transgenics, CRISPR, brain organoids

Imaging and Molecular Biology Platform (IMBP)

Scientific Director: Ajitha Thanabalasuriar
Faculty: Medicine and Health Sciences

The IMBP is a centralized resource for confocal/multiphoton and high content microscopy as well as molecular biology technologies for quantitative (qPCR) and qualitative (Bioanalyzer) sample analysis.

Keywords:Ìýlight microscopy, confocal, multiphoton, high content microscopy, molecular biology

Metabolomics Innovation Resource (MIR)

Scientific Director: Peter Siegel
Faculty: Medicine and Health Sciences

MIR offers expertise in high-quality and reproducible metabolic phenotyping. The platform provides advanced analytical capabilities and individual training programs, focusing on uncovering fundamental metabolic changes that contribute to various pathologies, including cancer.

Keywords:Ìýmetabolites, cellular respiration, MS, NMR, cancer

Surface Plasmon Resonance - Mass Spectrometry Facility (SPR-MS)

Scientific Directors: Jean-Francois Trempe, Gerhard Multhaup
Faculty: Medicine and Health Sciences

SPR-MS offers expertise in advanced protein biochemistry through a unique portfolio of integrated workflows, including Surface Plasmon Resonance (SPR), Mass Spectrometry (MS), and Multiplexed Immunoassays (SIMOA). These services accelerate the understanding of biomolecules in health and disease, aiding in therapeutic design.

Keywords:Ìýprotein-protein interaction, proteomics, Mass spectrometry, therapeutic design

º«¹úÂãÎè Advanced Therapies Research and Educational Centre (MATREC)

Scientific Director: Terry Hebert
Faculty: Medicine and Health Sciences

MATREC bridges the gap between preclinical research and clinical implementation by offering hands-on training in current good manufacturing practices (cGMP). It supports the production of advanced therapies and the modification of bioproduction protocols to meet clinical phase I or II standards.Ìý

Keywords:Ìýpreclinical research, clinical implementation, good manufacturing practices, bioproduction protocols

Genomics and RNA

Canadian Centre for Computational Genomics (C3G)

Scientific Director: Guillaume Bourque
Faculty: Medicine and Health Sciences

The C3G platform provides access to highly qualified bioinformatics and IT personnel who deliver customized data analyses, software development, data portals, computing infrastructure and training services.Ìý

Keywords: genomics, bioinformatics, data analysis, software development, HPC

º«¹úÂãÎè Applied Genomic Innocation Core (MAGIC)

Scientific Director: Mark Lathrop
Faculty: Medicine and Health Sciences

Dedicated to advancing multi-omics research, MAGIC provides state-of-the-art equipment and expertise to produce, manage and interpret large amounts of genomics data.Ìý

Keywords: genomics, sequencing, Next-Generation Sequencing, epigenomicsÌý

Imaging

Advanced BioImaging Facility (ABIF)

Scientific Director: Claire Brown
Faculty: Medicine and Health Sciences

The ABIF offers more than a dozen state-of-the-art light microscopy platforms and provides expert training and support from sample prep to imaging, image analysis and preparation of data for publication.​

Keywords: ​Light microscopy, confocal microscopy, live cell, super resolution, light sheet, image analysisÌý

Facility for Electron Microscopy Research (FEMR)

Scientific Director:ÌýJoaquin OrtegaÌý
Faculty: Medicine and Health Sciences

FEMR is a world-class, open-access electron microscopy (EM) facility that offers a comprehensive range of electron microscopy (EM) resources, expertise, and services for routine and advanced sample preparation, imaging, and analysis of biological and sensitive materials.Ìý

Keywords: EM sample preparation, EM imaging, EM analysis, Cryo EMÌý

Neuro Microcopy Core Facility (NMCF)

Scientific Director: Thomas Stroh
Faculty: Medicine and Health Sciences

Located at the Montreal Neurological Institute, the NMCF supports a broad range of imaging techniques, including confocal microscopy, Ca++ imaging, super resolution, and TIRF microscopy.Ìý

Keywords: confocal microscopy, calcium imaging, live cell, TIRF and super resolutionÌý

Imaging and Molecular Biology Platform (IMBP)

Scientific Director: Ajitha ThanabalasuriarÌý
Faculty: Medicine and Health Sciences

The IMBP is a centralized resource for confocal/multiphoton and high content microscopy as well as molecular biology technologies for quantitative (qPCR) and qualitative (Bioanalyzer) sample analysis.Ìý

Keywords: light microscopy, confocal, multiphoton, high content microscopy, molecular biology

Single Cell Imaging and Mass Cytometry Platform (SCIMAP)

Scientific Director: Logan Walsh
Faculty: Medicine and Health Sciences

SCIMAP provides advanced mass cytometry services for both liquid samples and tissue sections. The platform uses unique, well-validated antibody panels conjugated with heavy metals, enabling the simultaneous identification of over 40 markers on single cells.Ìý

Keywords: spatial biology, mass cytometry, antibody panels, marker profilingÌý

Materials and Manufacturing

º«¹úÂãÎè Nanotools Microfabrication Facility

Scientific Director: Peter Grutter
Faculty: Medicine and Health Sciences

Nanotools provides training, consultation, and access to specialized micro and nanofabrication tools. Acting as a 21st-century machine shop, it enables the fabrication, packaging, and characterization of nano- and micrometer-sized computer chips or microfluidic ‘lab-on-a-chip’ systems.Ìý

Keywords:Ìýnanofabrication, microfluidics, packaging, chips

Molecules and StructureÌý

Metabolomics Innovation Resource (MIR)

Scientific Director: Peter Siegel
Faculty: Medicine and Health Sciences

MIR offers expertise in high-quality and reproducible metabolic phenotyping. The platform provides advanced analytical capabilities and individual training programs, focusing on uncovering fundamental metabolic changes that contribute to various pathologies, including cancer.Ìý

Keywords: metabolites, cellular respiration, MS, NMR, cancerÌý

Centre for Structural Biology Research (Centre de Recherche en Biologie Structurale) (CRBS)

Scientific Director: Martin SchmeingÌý
Faculty: Medicine and Health Sciences

The CRBS platform offers state-of-the-art infrastructure for biophysical and structural biology research in combination with expert technical support and training to facilitate structure-function based research.Ìý

Keywords:Ìýbiophysics, proteomics, molecular structure, x-ray crystallography, cryo-EMÌý

Surface Plasmon Resonance - Mass Spectometry Facility (SPR-MS)

Scientific Director: Jean-Francois Trempe, Gerhard Multhaup
Faculty: Medicine and Health Sciences

SPR-MS offers expertise in advanced protein biochemistry through a unique portfolio of integrated workflows, including Surface Plasmon Resonance (SPR), Mass Spectrometry (MS), and Multiplexed Immunoassays (SIMOA). These services accelerate the understanding of biomolecules in health and disease, aiding in therapeutic design.Ìý

Keywords: protein-protein interaction, proteomics, Mass spectrometry, therapeutic designÌý

Facility for Electron Microscopy Research (FEMR)

Scientific Director: Joaquin Ortega
Faculty: Medicine and Health Sciences

FEMR is a world-class, open-access electron microscopy (EM) facility that offers a comprehensive range of electron microscopy (EM) resources, expertise, and services for routine and advanced sample preparation, imaging, and analysis of biological and sensitive materials.

Keywords: EM sample preparation, EM imaging, EM analysis, Cryo EM

Neuroscience

Clinical Biospecimen Imaging and Genetic Repository (C-BIG)

Scientific Director: Jason KaramchandaniÌý
Faculty: Medicine and Health Sciences

The C-BIG is a repository offering a collection of biospecimen samples, clinical information, imaging, and genetic data from individuals with neurological diseases and healthy controls. This data is available to researchers globally, adhering to The Neuro’s Open Science principles.Ìý

Keywords:Ìýrepository, biospecimen, neurological disorders, brainÌý

Early Drug Discovery Unit (EDDU)

Scientific Director: Thomas Durcan
Faculty: Medicine and Health Sciences

The EDDU uses patient-derived iPSCs to create 2D and 3D brain models, including organoids. They provide these materials and expertise to researchers for understanding and treating brain disorders, as well as for translational research and preclinical therapies.

Keywords:Ìýstem cells, transgenics, CRISPR, brain organoids

NeuroHub

Scientific Director: Jean-Baptiste Poline
Faculty: Medicine and Health Sciences

NeuroHub connects neuroscience with big data management. This unique platform allows users to collect, store and share data with colleagues or the community and to run complex tools and pipelines on high performance computing infrastructure.

Keywords:Ìýdata management, data storage, computing, neuroscience

The NeuroMicroscopy Core Facility (NMCF)

Scientific Director: Thomas Stroh
Faculty: Medicine and Health Sciences

Located at the Montreal Neurological Institute, the NMCF supports a broad range of imaging techniques, including confocal microscopy, Ca++ imaging, super resolution, and TIRF microscopy.

Keywords:Ìýconfocal microscopy, calcium imaging, live cell, TIRF and super resolution

Transgenics and Models of Disease

º«¹úÂãÎè Integrated Core for Animal Modeling (MICAM)

Scientific Director: Yojiro Yamanaka
Faculty: Medicine and Health Sciences

MICAM provides expertise in CRISPR/Cas9-mediated genome engineering, cryopreservation, IVF, rederivation to model human disease, study biological processes and test therapies.Ìý

Keywords:Ìýanimal models, transgenics, CRISPR, genome engineering, IVFÌý

Early Drug Discovert Unit (EDDU)

Scientific Director: Thomas Durcan
Faculty: Medicine and Health Sciences

The EDDU uses patient-derived iPSCs to create 2D and 3D brain models, including organoids. They provide these materials and expertise to researchers for understanding and treating brain disorders, as well as for translational research and preclinical therapies.

Keywords:Ìýstem cells, transgenics, CRISPR, brain organoids

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