Nathan Luedtke

Academic title(s): 

Professor

Nathan Luedtke
Branch: 
Université
Department: 
Chimie
Areas of expertise: 
  • Precision oncology
  • Small activating RNA and mRNA
  • Chemical biology and medicinal chemistry
  • Fluorescent probe and diagnostics development
  • Nucleoside, nucleotide and oligonucleotide synthesis
Biography: 

Nathan Luedtke’s group pioneered the development of non-toxic, catalyst-free bioorthogonal “click” reactions on cellular DNA and RNA. In cooperation with Sigma Aldrich, the “clickable” nucleosides produced in the Luedtke Lab have been commercialized and distributed world-wide. This has facilitated broad use of Luedtke’s molecules and methods in highly diverse research fields including biomaterials, chromosomal architecture, RNA therapeutics, stem cell biology, virology, and precision medicine.
Luedtke’s leadership and service in the field of nucleic acids chemistry is reflected by his activities on various editorial boards of journals, including Molecules, Chimia, and Nature Signal Transduction and Targeted Therapy. A commitment to service is further reflected by his organization of numerous international symposia, including the Albert Hofmann Symposium, Light and Medicine, Methods and Applications in Fluorescence, as well as his tenure on the D2R Partner and Community Engagement Committee and as the president of the Hans E. Schmid Foundation for supporting and promoting young scientists who are pursuing original research in organic chemistry. He is currently a James Professor and hold appointments in the Department of Chemistry, and the Department of Pharmacology and Therapeutics at .

Projects: 

D2R Projects

Principal Investigator

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