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Dr. Nader Sadeghi

Academic title(s): 
  • Professor and Chair, Department of Otolaryngology - Head and Neck Surgery º«¹úÂãÎè
  • Professor, Department of Oncology, º«¹úÂãÎè 
  • Director of º«¹úÂãÎè Head and Neck Cancer Program 
Dr. Nader Sadeghi
Contact Information
Email address: 
nader.sadeghi [at] mcgill.ca
Department: 
Otolaryngology
Division: 
Surgical and Interventional Sciences
Degree(s): 

MD

Location: 
º«¹úÂãÎè Health Centre (MUHC - Glen) - Royal Victoria Hospital
Graduate supervision: 

Currently supervising students

Group: 
Currently Recruiting
M.Sc. Students
M.Sc. Non-Thesis projects
Research areas: 
Surgical Outcomes and Quality
Regenerative Medicine
Surgical Oncology
Translation and Innovation
Medical Technology
Current research: 

Development of novel therapeutic strategies for oral and throat cancer 

Clinical Interests: 
  • Transoral Robotic Surgery 
  • Transoral Laser Microsurgery 
  • Head and Neck Oncology 
  • Salivary gland surgery 
  • Head and Neck Endocrine Surgery 
Areas of interest: 

Neoadjuvant Chemotherapy and Transoral Robotic Surgery for oropharyngeal cancer (NECTORS trial), Robotic surgery in head and neck cancer, cancer biology, human papilloma virus (HPV) and head and neck cancer, liquid biopsy, quality of life and outcomes in head and neck cancer, clinical trials, tumor immune micro-environment 

Biography: 

Dr. Sadeghi presently serves as the Chairman in the Department of Otolaryngology - Head and Neck Surgery at º«¹úÂãÎè.  He is also the Chief of the Department of Otolaryngology - Head and Neck Surgery at the MUHC, and Director of º«¹úÂãÎè Head and Neck Cancer Program. 

Dr. Sadeghi graduated from º«¹úÂãÎè Medicine in 1991.  He completed his residency at º«¹úÂãÎè followed by a research fellowship.  He then completed a fellowship training in Head and Neck Oncology Surgery at Rush-Presbyterian-St. Luke's Medical Center in Chicago, IL.  Following his early career at º«¹úÂãÎè, he moved to the George Washington University in Washington, DC, where he served as Professor of Surgery and Director of Head and Neck Surgery.  In 2017, he returned to º«¹úÂãÎè to lead the department. 

Dr.Sadeghi’s research focuses on head and neck cancer and in particular on development of novel therapeutic strategies for oral and throat cancer. I focus on harnessing advances in systemic therapies and minimally invasive robotic surgery to develop novel combinations allowing effective cancer control and minimizing chronic therapy-related toxicity. Through adaptive clinical trials starting with systemic therapy, I am investigating a personalized adaptive approach for surgical treatment of oral and throat cancer. I am investigating molecular determinants of cancer response to chemotherapy to help design personalized treatment with a focus on cancer cure while preserving quality of life and functional outcome after cancer treatment. 

Selected publications: 

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