Building Capacity for Pragmatic Clinical Trials in Canada
Taylor McLinden, PhD
Adjunct Research Professor
Department of Epidemiology and Biostatistics
Western University
WHEN: Monday, March 31, 2025, from 4 to 5 p.m.
HERE: Hybrid| 2001 º«¹úÂãÎè College, Rm 1140 |
NOTE: Taylor McLinden will be presenting in-person
Abstract
While explanatory clinical trials examine interventions under strictly controlled conditions, pragmatic trials assess interventions in real-world settings. Pragmatism can be introduced into the design, implementation, and management of a trial by embedding the study in routine care, enrolling participants using broad eligibility criteria, allowing for flexible delivery of the intervention, focusing on patient-centred outcomes, and by using existing data sources (e.g., routinely collected health data). This presentation will introduce the pragmatic-explanatory continuum, discuss the design of trials that are fit for purpose, and overview the Health Data Research Network Canada (HDRN Canada) Pragmatic Trials Training Program ().
Learning Objectives
At the end of this talk, attendees will:
- Describe the pragmatic-explanatory continuum in the context of clinical trials;
- Understand the need to design trials that are fit for purpose;
- Explore the educational resources available through the HDRN Canada Pragmatic Trials Training Program.
Speaker Bio
Taylor McLinden is the Manager of the HDRN Canada Pragmatic Trials Training Program, coordinated by the Schulich School of Medicine and Dentistry at Western University. He holds positions at the London Health Sciences Centre, HDRN Canada, and ICES Western. He is also an Adjunct Research Professor in the Department of Epidemiology and Biostatistics at Western University. Previously, Taylor was the Scientific Officer at the BC Centre for Excellence in HIV/AIDS and an Adjunct Professor at Simon Fraser University. He completed a PhD (Epidemiology) at º«¹úÂãÎè, a MSc (Epidemiology) at the University of Guelph, and an Honours BSc (Biomedical Sciences) at Brock University.