Natalie Zeytuni
- Assistant Professor, Department of Anatomy and Cell Biology, º«¹úÂãÎè
- Co-Associate Director - The Centre de Recherche en Biologie Structurale, º«¹úÂãÎè
![Natalie Zeytuni Natalie Zeytuni](/microimm/files/microimm/styles/medium_focal__220_x_220_/public/natalie_zeytuni_-_headshot.jpg?itok=kG2OTHCi)
Research Interests:
- Structural biology of bacterial systems
- Membrane transporters and secretion systems
- Oral pathogens and their role in host-pathogen interactions
- Novel therapeutic approaches targeting bacterial virulence
- Cryo-electron microscopy and X-ray crystallography
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Dr. Natalie Zeytuni’s lab focuses on the structural and functional characterization of bacterial systems that play critical roles in health and disease. A key area of interest is oral pathogens, which are major contributors to periodontal disease and systemic infections. By studying the molecular mechanisms of these pathogens, the lab aims to uncover their strategies for colonization, persistence, and virulence.
The research combines advanced structural biology techniques, such as cryo-electron microscopy (cryo-EM) and X-ray crystallography, with biochemical, microbiological, and genetic approaches to:
- Decipher the molecular architecture of secretion systems and membrane transporters in oral pathogens.
- Understand how these systems contribute to microbial biofilm formation, antibiotic resistance, and immune evasion.
- Develop novel therapeutic strategies to mitigate the impact of oral pathogens on human health.
This research has broad implications, from improving oral health to addressing systemic diseases linked to oral infections.
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